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Article

Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver.

Frontiers in immunology - 1 Jan 2023

Hernández-Banqué Carles, Jové-Juncà Teodor, Crespo-Piazuelo Daniel, González-Rodríguez Olga, Ramayo-Caldas Yuliaxis, Esteve-Codina Anna, Mercat Marie-José, Bink Marco C A M, Quintanilla Raquel, Ballester Maria

Abstract excerpt

C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, little is known about the molecular mechanisms that control pig CRP gene expression. The main goal of the present work was to study the regulatory mechanisms and identify functional genetic variants regulating...

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Identifiers

PMID: 37781386
DOI: 10.3389/fimmu.2023.1250942
PMCID: PMC10539928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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