Article
New variants including ARG1 polymorphisms associated with C-reactive protein levels identified by genome-wide association and pathway analysis.
PloS one - 1 Jan 2014
Vinayagamoorthy Nadimuthu, Hu Hae-Jin, Yim Seon-Hee, Jung Seung-Hyun, Jo Jaeseong, Jee Sun Ha, Chung Yeun-Jun
Abstract excerpt
C-reactive protein (CRP) is a general marker of systemic inflammation and cardiovascular disease (CVD). The genetic contribution to differences in CRP levels remains to be explained, especially in non-European populations. Thus, the aim of this study was to identify genetic loci associated with CRP levels in Korean population. We performed genome-wide association studies (GWAS) using SNPs from 8,529 Korean...
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