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Natural Nrf2 Inhibitors: A Review of Their Potential for Cancer Treatment

1 Jan 2023

Abstract excerpt

Nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that regulates redox homeostasis, plays a pivotal role in several cellular processes such as cell proliferation and survival, and has been found to be aberrantly activated in many cancers. As one of the key oncogenes, Nrf2 represents an important therapeutic target for cancer treatment. Research has unraveled the main mechanisms underlying...

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PMID: 37416770
DOI: 10.7150/ijbs.82401

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