Glucocorticoid Receptor Gene (NR3C1) Polymorphisms and Metabolic Syndrome: Insights from the Mennonite Population.

doi:10.3390/genes14091805

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Glucocorticoid Receptor Gene (NR3C1) Polymorphisms and Metabolic Syndrome: Insights from the Mennonite Population.

Genes - 15 Sept 2023

Kolb Kathleen Liedtke, Mira Ana Luiza Sprotte, Auer Eduardo Delabio, Bucco Isabela Dall'Oglio, de Lima E Silva Carla Eduarda, Dos Santos Priscila Ianzen, Hoch Valéria Bumiller-Bini, Oliveira Luana Caroline, Hauser Aline Borsato, Hundt Jennifer Elisabeth, Shuldiner Alan R, Lopes Fabiana Leão, Boysen Teide-Jens, Franke Andre, Pinto Luis Felipe Ribeiro, Soares-Lima Sheila Coelho, Kretzschmar Gabriela Canalli, Boldt Angelica Beate Winter

Abstract excerpt

The regulation of the hypothalamic-pituitary-adrenal (HPA) axis is associated with polymorphisms and the methylation degree of the glucocorticoid receptor gene (NR3C1) and is potentially involved in the development of metabolic syndrome (MetS). In order to evaluate the association between MetS with the polymorphisms, methylation, and gene expression of the NR3C1 in the genetically isolated Brazilian Mennonite...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Digestive system and related health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Ethnicity

Share to Genetic Associations and Epidemiology

Share to Genotype

Share to Glucocorticoids

Share to Metabolic Syndrome

Share to Receptors, Glucocorticoid

Source

Open in PubMed Open full text

Identifiers

PMID: 37761945
DOI: 10.3390/genes14091805
PMCID: PMC10530687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid Receptor Gene (NR3C1) Polymorphisms and Metabolic Syndrome: Insights from the Mennonite Population.PMID 37761945Read ↗

Polymorphisms in NR3C1 gene associated with risk of metabolic syndrome in a Chinese population.Semantic proximity Read ↗

HPA axis dysregulation, NR3C1 polymorphisms and glucocorticoid receptor isoforms imbalance in metabolic syndrome.Semantic proximity Read ↗

Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome.Semantic proximity Read ↗

[Association of the structure of the glucocorticoid receptor and single nucleotide NR3C1 gene polymorphisms with metabolic disorders].Semantic proximity Read ↗

Novel genetic polymorphisms in the NR3C1 (glucocorticoid receptor) gene in a Japanese population.Semantic proximity Read ↗

The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men.Semantic proximity Read ↗

DNA methylation: conducting the orchestra from exposure to phenotype?Semantic proximity Read ↗

Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: A critical reviewSemantic proximity Read ↗

A genomic study of the Japanese population focusing on the glucocorticoid receptor interactome highlights distinct genetic characteristics associated with stress responseSemantic proximity Read ↗

Genetic Associations and Interactions Between the NR3C1 (GR) and NR3C2 (MR) Genes in Schizophrenia.Semantic proximity Read ↗

MR and GR functional SNPs may modulate tobacco smoking susceptibility.Semantic proximity Read ↗

A Genomic Study of the Japanese Population Focusing on the Glucocorticoid Receptor Interactome Highlights Distinct Genetic Characteristics Associated with Stress Response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.