Article
A Genomic Study of the Japanese Population Focusing on the Glucocorticoid Receptor Interactome Highlights Distinct Genetic Characteristics Associated with Stress Response.
Advances in experimental medicine and biology - 1 Jan 2023
Mitsis Thanasis, Papageorgiou Louis, Papakonstantinou Eleni, Diakou Io, Pierouli Katerina, Dragoumani Konstantina, Bacopoulou Flora, Kino Tomoshige, Chrousos George P, Eliopoulos Elias, Vlachakis Dimitrios
Abstract excerpt
All living organisms have been programmed to maintain a complex inner equilibrium called homeostasis, despite numerous adversities during their lifespan. Any threatening or perceived as such stimuli for homeostasis is termed a stressor, and a highly conserved response system called the stress response system has been developed to cope with these stimuli and maintain or reinstate homeostasis. The glucocorticoid...
Topics
- Humans
- East Asian People
- Genomics
- Molecular Chaperones
- Polymorphism, Single Nucleotide
- Receptors, Glucocorticoid
