Article
Escitalopram Personalized Dosing: A Population Pharmacokinetics Repository Method.
Drug design, development and therapy - 1 Jan 2023
Liu Xin, Ju Gehang, Yang Wenyu, Chen Lulu, Xu Nuo, He Qingfeng, Zhu Xiao, Ouyang Dongsheng
Abstract excerpt
Escitalopram (SCIT) represents a first-line antidepressant and antianxiety medication. Pharmacokinetic studies of SCIT have demonstrated considerable interindividual variability, emphasizing the need for personalized dosing. Accordingly, we aimed to create a repository of parametric population pharmacokinetic (PPK) models of SCIT to facilitate model-informed precision dosing. In November 2022, we searched PubMed,...
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