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Article

Effect of age, weight, and CYP2C19 genotype on escitalopram exposure.

Journal of clinical pharmacology - 1 Jan 2010

Jin Yuyan, Pollock Bruce G, Frank Ellen, Cassano Giovanni B, Rucci Paola, Müller Daniel J, Kennedy James L, Forgione Rocco Nicola, Kirshner Margaret, Kepple Gail, Fagiolini Andrea, Kupfer David J, Bies Robert R

Abstract excerpt

The purpose of this study was to characterize escitalopram population pharmacokinetics (PK) in patients treated for major depression in a cross-national, US-Italian clinical trial. Data from the 2 sites participating in this trial, conducted at Pittsburgh (United States) and Pisa (Italy), were used. Patients received 5, 10, 15, or 20 mg of escitalopram daily for a minimum of 32 weeks. Nonlinear mixed effects...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19841156
DOI: 10.1177/0091270009337946
PMCID: PMC3571021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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