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Article

The binding profile of SARS-CoV-2 with human leukocyte antigen polymorphisms reveals critical alleles involved in immune evasion.

Journal of medical virology - 1 Sept 2023

Zhan Yan, Ye Ling, Ouyang Qianying, Yin Jiye, Cui Jiajia, Liu Ke, Guo Chengxian, Zhang Haibo, Zhai Jingbo, Zheng Chunfu, Guo Aoxiang, Sun Bao

Abstract excerpt

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), astonished the world and led to millions of deaths. Due to viral new mutations and immune evasion, SARS-CoV-2 ranked first in transmission and influence. The binding affinity of human leukocyte antigen (HLA) polymorphisms to SARS-CoV-2 might be related to immune escape, but the mechanisms remained unclear. In this...

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Identifiers

PMID: 37750416
DOI: 10.1002/jmv.29113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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