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Possible role of HLA class-I genotype in SARS-CoV-2 infection and progression: A pilot study in a cohort of Covid-19 Spanish patients.

Clinical immunology (Orlando, Fla.) - 1 Oct 2020

Iturrieta-Zuazo Ignacio, Rita Claudia Geraldine, García-Soidán Ana, de Malet Pintos-Fonseca Ana, Alonso-Alarcón Nieves, Pariente-Rodríguez Roberto, Tejeda-Velarde Amalia, Serrano-Villar Sergio, Castañer-Alabau José Luis, Nieto-Gañán Israel

Abstract excerpt

Human Leukocyte Antigen (HLA) includes a large set of genes with important actions in immune response against viral infection. Numerous studies have revealed the existence of significant associations between certain HLA alleles and the susceptibility and prognosis of different infectious diseases. In this pilot study we analyse the binding affinity between 66 class I HLA alleles and SARS-CoV-2 viral peptides, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32810602
DOI: 10.1016/j.clim.2020.108572
PMCID: PMC7428760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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