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Bioinformatics Prediction and Identification of Sars-Cov-2-Derived Hla-a-Binding T Cell Epitopes

2023-06-13

Abstract excerpt

T cell immunity is the core component for effective control of SARS-CoV-2 infection. Identification of epitopes that specifically activate T cell immunity helps facilitate vaccine and diagnostic tools development against SARS-CoV-2. Here, we selected 47 peptides corresponding to 15 HLA-A isoforms based on bioinformatics algorithms and detected T cell responses with ELISPOT assays in vitro from 31 COVID-19 convales...

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Literature Corpus work
a6590e0b-6504-5013-8223-6d6386254d9a
DOI
10.2139/ssrn.4471955
Open publication

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Bioinformatics Prediction and Identification of Sars-Cov-2-Derived Hla-a-Binding T Cell EpitopesDOI 10.2139/ssrn.4471955
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