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Article

T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations.

Nucleic acids research - 7 Jan 2022

Nersisyan Stepan, Zhiyanov Anton, Shkurnikov Maxim, Tonevitsky Alexander

Abstract excerpt

Rapidly appearing SARS-CoV-2 mutations can affect T cell epitopes, which can help the virus to evade either CD8 or CD4 T-cell responses. We developed T-cell COVID-19 Atlas (T-CoV, https://t-cov.hse.ru) - the comprehensive web portal, which allows one to analyze how SARS-CoV-2 mutations alter the presentation of viral peptides by HLA molecules. The data are presented for common virus variants and the most frequent...

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Identifiers

PMID: 34396391
DOI: 10.1093/nar/gkab701
PMCID: PMC8385993

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