Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms

10 May 2021

Abstract excerpt

Given the highly polymorphic nature of Human Leukocyte Antigen (HLA) molecules, it is not surprising that they function as key regulators of the host immune response to almost all invading pathogens, including SARS-CoV-2, the etiological agent responsible for the recent COVID-19 pandemic. Several correlations have already been established between the expression of a specific HLA allele/haplotype and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Inflammasome and immune disorders
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34116863
DOI: 10.1016/j.humimm.2021.05.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphismsPMID 34116863Read ↗

Current HLA Investigations on SARS-CoV-2 and PerspectivesSemantic proximity Read ↗

Bioinformatic HLA Studies in the Context of SARS-CoV-2 Pandemic and Review on Association of HLA Alleles with Preexisting Medical Conditions.Semantic proximity Read ↗

Possible role of HLA class-I genotype in SARS-CoV-2 infection and progression: A pilot study in a cohort of Covid-19 Spanish patients.Semantic proximity Read ↗

Features of HLA class I expression and its clinical relevance in SARS-CoV-2: What do we know so far?Semantic proximity Read ↗

Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level.Semantic proximity Read ↗

Association between HLA gene polymorphisms and mortality of COVID-19: An in silico analysis.Semantic proximity Read ↗

HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 eraSemantic proximity Read ↗

T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations.Semantic proximity Read ↗

HLA repertoire of 115 UAE nationals infected with SARS-CoV-2.Semantic proximity Read ↗

The association of human leucocyte antigen (HLA) alleles with COVID-19 severity: A systematic review and meta-analysis.Semantic proximity Read ↗

The binding profile of SARS-CoV-2 with human leukocyte antigen polymorphisms reveals critical alleles involved in immune evasion.Semantic proximity Read ↗

The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.