Article
Screening for K13-Propeller Mutations Associated with Artemisinin Resistance in Plasmodium falciparum in Yambio County (Western Equatoria State, South Sudan).
The American journal of tropical medicine and hygiene - 1 Nov 2023
Molina-de la Fuente Irene, Sagrado Benito María José, Ousley Janet, Gisbert Francisco de Bartolomé, García Luz, González Vicenta, Benito Agustín, Chol Buai Tut, Julla Ahmed, Bakri Abubakr, Nanclares Carolina, Berzosa Pedro
Abstract excerpt
Artemisinin-combined treatments are the recommended first-line treatment of Plasmodium falciparum malaria, but they are being threatened by emerging artemisinin resistance. Mutations in pfk13 are the principal molecular marker for artemisinin resistance. This study characterizes the presence of mutations in pfk13 in P. falciparum in Western Equatoria State, South Sudan. We analyzed 468 samples from patients with...
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