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Article

Novel pfk13 polymorphisms in Plasmodium falciparum population in Ghana.

Scientific reports - 12 May 2022

Matrevi Sena Adzoa, Tandoh Kwesi Zandoh, Bruku Selassie, Opoku-Agyeman Philip, Adams Tryphena, Ennuson Nana Aba, Asare Bright, Hagan Oheneba Charles Kofi, Abuaku Benjamin, Koram Kwadwo Ansah, Fox Ann, Quashie Neils Ben, Letizia Andrew G, Duah-Quashie Nancy Odurowah

Abstract excerpt

The molecular determinants of Plasmodium falciparum artemisinin resistance are the single nucleotide polymorphisms in the parasite's kelch propeller domain, pfk13. Validated and candidate markers are under surveillance in malaria endemic countries using artemisinin-based combination therapy. However, pfk13 mutations which may confer parasite artemisinin resistance in Africa remains elusive. It has therefore...

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Identifiers

PMID: 35551239
DOI: 10.1038/s41598-022-11790-9
PMCID: PMC9098865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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