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Article

Hypomethylation of DRD2 promotes breast cancer through the FLNA-ERK pathway

9 Sept 2023

Abstract excerpt

We investigated the effect of stem cell marker dopamine receptor D2 (DRD2) on the proliferation of hormone-receptor-negative breast cancer cells. High-throughput DNA methylation sequencing on an 850 K chip was used to pre-screen breast cancer tissues with significant methylation differences. The expression of DRD2 in breast cancer and normal breast tissues, and clinical risk factors, were detected by...

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PMID: 37729778
DOI: 10.1016/j.cancergen.2023.09.001

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