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Article

Nutritional Sensor REDD1 in Cancer and Inflammation: Friend or Foe?

26 Aug 2022

Abstract excerpt

Regulated in Development and DNA Damage Response 1 (REDD1)/DNA Damage-Induced Transcript 4 (DDIT4) is an immediate early response gene activated by different stress conditions, including growth factor depletion, hypoxia, DNA damage, and stress hormones, i.e., glucocorticoids. The most known functions of REDD1 are the inhibition of proliferative signaling and the regulation of metabolism via the repression of the...

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PMID: 36077083
DOI: 10.3390/ijms23179686

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