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Evolution of the T4 phage virion is driven by selection pressure from non-bacterial factors

19 Sept 2023

Abstract excerpt

ABSTRACT Bacteriophages colonize animal and human bodies, propagating on sensitive bacteria that are symbionts, commensals, or pathogens of animals and humans. T4-like phages are dependent on abundant symbionts such as Escherichia coli , commonly present in animal and human gastrointestinal (GI) tracts. Bacteriophage T4 is one of the most complex viruses, and its intricate structure, particularly the capsid head...

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PMID: 37724862
DOI: 10.1128/spectrum.00115-23

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