Article
Modular architecture of the T4 phage superfamily: a conserved core genome and a plastic periphery.
Virology - 5 Jun 2007
Comeau André M, Bertrand Claire, Letarov Andrei, Tétart Françoise, Krisch H M
Abstract excerpt
Among the most numerous objects in the biosphere, phages show enormous diversity in morphology and genetic content. We have sequenced 7 T4-like phages and compared their genome architecture. All seven phages share a core genome with T4 that is interrupted by several hyperplastic regions (HPRs) where most of their divergence occurs. The core primarily includes homologues of essential T4 genes, such as the virion...
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