Article

Convergent Cysteine Enrichment in Diverse Gut Phage Capsids Suggests Gut-Associated Structural Adaptation

2026-07-04

Abstract excerpt

<h4>Background</h4> The gut environment is hostile to life, yet the human virome, dominated by bacteriophages, persists. Adaptations to the major capsid protein (MCP) may explain this. Phage MCPs conserve the HK97 fold, ideal for detecting convergent features across phage populations. Prior capsid stability research focused on individual phages, limiting broader pattern identification. <h4>Methods</h4> MCPs from...

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Literature Corpus work: c1e4e02a-2139-57a0-9c03-102728983643
DOI: 10.64898/2026.07.03.736451

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