Article

<i>Eggerthella lenta</i> evades bacteriophage through reversible megabase-scale inversions of capsular polysaccharide gene clusters

2026-04-25

Abstract excerpt

<h4>SUMMARY</h4> Bacteriophages are a promising tool for microbiome editing, yet their development has been constrained by limited insights into bacteriophage-host interactions within their shared mammalian body habitat. We isolated a lytic phage ΦKL11 that efficiently targets a disease-associated member of the human gut microbiota, Eggerthella lenta , during in vitro growth. However, ΦKL11 selects for a pre-ex...

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Literature Corpus work: fc17207c-aada-54c1-ad3c-3d0386c63d5c
DOI: 10.64898/2026.04.24.720693

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