Article
Bacteriophages evolve enhanced persistence to a mucosal surface.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 2022
Chin Wai Hoe, Kett Ciaren, Cooper Oren, Müseler Deike, Zhang Yaqi, Bamert Rebecca S, Patwa Ruzeen, Woods Laura C, Devendran Citsabehsan, Korneev Denis, Tiralongo Joe, Lithgow Trevor, McDonald Michael J, Neild Adrian, Barr Jeremy J
Abstract excerpt
The majority of viruses within the gut are obligate bacterial viruses known as bacteriophages (phages). Their bacteriotropism underscores the study of phage ecology in the gut, where they modulate and coevolve with gut bacterial communities. Traditionally, these ecological and evolutionary questions were investigated empirically via in vitro experimental evolution and, more recently, in vivo models were adopted...
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