Article
Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract
2020-07-20
Abstract excerpt
The human mucosal surface consists of a eukaryotic epithelium, a prokaryotic microbiota, and a carbohydrate-rich interface that separates them. Bacteriophage parasitize the prokaryotes but are not known to associate with eukaryotic cells. In the gastrointestinal tract, the interaction of these two domains influences the health of the host, especially colonization with invasive pathobionts. Antibiotics may be used...
Topics
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- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- Glycosylation and Glycoproteins Research
- Gut microbiota and health
- Microbial infections and disease research
- Monoclonal and Polyclonal Antibodies Research
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
Identifiers and source
- Literature Corpus work
- 49d9a652-9640-544f-8866-3b04967065e1
- DOI
- 10.1101/2020.07.20.212829
