Article

Drug classes affecting intracranial aneurysm risk: genetic correlation and Mendelian randomization

2023-10-25

Abstract excerpt

<h4>Abstract and key words</h4> <h4>Background</h4> There is no non-invasive treatment option to prevent aneurysmal subarachnoid hemorrhage (ASAH) caused by intracranial aneurysm (IA) rupture. We aimed to identify drug classes that may affect liability to IA using a genetic approach. <h4>Methods</h4> We obtained genome-wide association summary statistics for unruptured IA (N=2,140 cases), ASAH (N=5,140 cases), and...

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Literature Corpus work: 5f0cd515-0cd5-52d6-be45-493530d85dd7
DOI: 10.1101/2023.10.23.23297443

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