Article
Multiplex genotyping of SNPs in genomic DNA via hydrogel-based assay mediated with MutS and polyethylene glycol.
Biosensors & bioelectronics - 1 Dec 2023
Mun Seok Joon, Jang Wookyoung, Park Hyun-Seung, Lim Yong Jun, Yang Tae-Jin, Bong Ki Wan
Abstract excerpt
The simultaneous genotyping of multiple single nucleotide polymorphisms (SNPs) in genomic DNA derived from organisms holds significant potential for applications such as precision medicine and food product authentication. However, conventional assay technologies including qPCR-based techniques, microarrays, and hydrogel-based assays face limitations in efficient multiplexing of SNPs, particularly for large-size...
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