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Article

Encoded hydrogel microparticles with universal mismatch-incorporated DNA probes for highly specific multiplex detection of SNPs.

Talanta - 1 Aug 2022

Moon Hyun June, Mun Seok Joon, Lee Jun Ho, Roh Yoon Ho, Lim Yong Jun, Bong Ki Wan

Abstract excerpt

Hydrogel microparticle-based nucleic acid assays are an attractive detection platform based on their multiplexing capabilities with high sensitivity and specificity. A particular area of interest is single-nucleotide polymorphism (SNP) sensing, where multiple SNPs should be identified in a highly reliable yet economical manner. However, hydrogel microparticles leveraging probe-target hybridization as a key...

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PMID: 35462139
DOI: 10.1016/j.talanta.2022.123480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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