Article
An alcohol dehydrogenase 7 gene polymorphism associates with both acute and chronic pain in sickle cell disease.
Pharmacogenomics - 1 Aug 2023
Kashyap Yavnika, He Ying, Sadhu Nilanjana, Yao Yingwei, Wilkie Diana J, Molokie Robert E, Wang Zaijie Jim
Abstract excerpt
Introduction: As the most distressing complication of sickle cell disease (SCD), pain is marked by considerable heterogenicity. In this study we explored the potential association of alcohol dehydrogenase 7 gene (ADH7) polymorphism rs971074 with sickle cell pain. Methods: We analyzed clinical phenotypes and the rs971074 single-nucleotide polymorphism in ADH7 by MassARRAY-iPlex analysis in a cohort of SCD...
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