Article
Evaluating Associations between Average Pain Intensity and Genetic Variation in People with Sickle Cell Disease: An Exploratory Study.
Pain management nursing : official journal of the American Society of Pain Management Nurses - 1 Feb 2023
Knisely Mitchell R, Yang Qing, Stauffer Nic, Kenney Martha, Ashley-Koch Allison, Myers John, Walker Julia K L, Tanabe Paula J, Shah Nirmish R
Abstract excerpt
BACKGROUND: Pain is one of the most common and deleterious symptoms experienced by individuals with sickle cell disease (SCD). There is a paucity of studies identifying potential genetic mechanisms of pain in this population. AIM: Examine associations between 11 functional single nucleotide polymorphisms in 9 candidate genes with reports of average pain intensity in individuals with sickle cell disease. METHOD:...
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