Article
Vasopressin SNP pain factors and stress in sickle cell disease.
PloS one - 1 Jan 2019
Powell-Roach Keesha L, Yao Yingwei, Jhun Ellie H, He Ying, Suarez Marie L, Ezenwa Miriam O, Molokie Robert E, Wang Zaijie Jim, Wilkie Diana J
Abstract excerpt
PURPOSE: Frequencies of single nucleotide polymorphisms (SNPs) from pain related candidate genes are available for individuals with sickle cell disease (SCD). One of those genes, the arginine vasopressin receptor 1A gene (AVPR1A) and one of its SNPs, rs10877969, has been associated with pain and disability in other pain populations. In patients with SCD, clinical factors such as pain and stress have been...
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