Article
Phenotypic polarization of macrophages in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2013
Leitinger Norbert, Schulman Ira G
Abstract excerpt
Macrophages orchestrate the inflammatory response in inflamed tissues, and recent work indicates that these cells can alter their phenotypes and functions accordingly in response to changes in the microenvironment. Initial work in models of cardiovascular disease used immunologic markers to characterize macrophage phenotypes present in atherosclerotic plaque, and these studies have lately been extended through...
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