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Article

Chronic inflammation and vascular cell plasticity in atherosclerosis.

Nature cardiovascular research - 1 Dec 2024

Lin Alexander, Miano Joseph M, Fisher Edward A, Misra Ashish

Abstract excerpt

Vascular smooth muscle cells, endothelial cells and macrophages undergo phenotypic conversions throughout atherosclerosis progression, both as a consequence of chronic inflammation and as subsequent drivers of it. The inflammatory hypothesis of atherosclerosis has been catapulted to the forefront of cardiovascular research as clinical trials have shown that anti-inflammatory therapy reduces adverse cardiovascular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39653823
DOI: 10.1038/s44161-024-00569-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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