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SEOM clinical guidelines in Hereditary Breast and ovarian cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Dec 2015

Llort G, Chirivella I, Morales R, Serrano R, Sanchez A Beatriz, Teulé A, Lastra E, Brunet J, Balmaña J, Graña B

Abstract excerpt

Approximately, 7 % of all breast cancers (BC) and 11-15 % of ovarian cancers (OC) are associated with inherited predisposition, mainly related to germline mutations in high penetrance BRCA1/2 genes. Clinical criteria for genetic testing are based on personal and family history to estimate a minimum 10 % detection rate. Selection criteria are evolving according to new advances in this field and the clinical...

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Identifiers

PMID: 26669313
DOI: 10.1007/s12094-015-1435-3
PMCID: PMC4689749

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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