Article
The roles of apolipoprotein E ε4 on neuropathology and neuroinflammation in patients with Alzheimer's disease.
CNS neuroscience & therapeutics - 1 Mar 2024
He Mingyue, Lian Tenghong, Guo Peng, Zhang Weijiao, Zhang Yanan, Huang Yue, Liu Gaifen, Guan Huiying, Li Jinghui, Luo Dongmei, Zhang Weijia, Zhang Wenjing, Qi Jing, Yue Hao, Wang Xiaomin, Zhang Wei
Abstract excerpt
AIMS: To explore the roles of apolipoprotein E (APOE) ε4 on the neuropathology and neuroinflammation in Alzheimer's disease (AD) patients. METHODS: AD patients were divided into the APOE ε4 carrier and the APOE ε4 non-carrier groups according to APOE genotype. Demographic information, cognitive function, the levels of neuropathological proteins and neuroinflammatory factors in cerebrospinal fluid (CSF) were...
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