Article
APOE ε4 allele elevates the expressions of inflammatory factors and promotes Alzheimer's disease progression: A comparative study based on Han and She populations in the Wenzhou area.
Brain research bulletin - 1 Jun 2017
Fan Yin-Ying, Cai Qiao-Le, Gao Zhi-Yong, Lin Xue, Huang Qi, Tang Wei, Liu Jia-Hong
Abstract excerpt
OBJECTIVE: This study aimed to investigate the impact of apolipoprotein E 4 (APOE4) gene polymorphisms on the expressions of inflammatory factors and the progression of Alzheimer's disease (AD). METHODS: A total of 185 AD patients (the case group, 130 cases from the Han ethnic group and 55 cases from the She ethnic group) and 190 healthy individuals (the control group, 130 cases from the Han ethnic group and 60...
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