Article
Case control study: G-allele of rs4244165 in JAK1 gene correlated with high-level brief psychiatric rating scale in bipolar patients.
Medicine - 15 Sept 2023
Benkortbi Elouaer Akila Ahlem Elouaer, Ben Mohamed Bochra, Zaafrane Ferid, Gaha Lotfi, Bel Hadj Jrad Tensaout Besma
Abstract excerpt
Bipolar disorder (BD) is a chronic and clinically complex disease, characterized by pathological disturbances in mood and energy. Cytokines can access the brain and their signaling pathways affect brain functions, such as neurotransmitter metabolism, neuroendocrine function, neural/synaptic plasticity, and mood neural circuitry. JAK 1 is the most common phosphorylation protein combined with the tyrosine kinase...
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