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Article

Association between bipolar I disorder and the L55M and Q192R polymorphisms of the paraoxonase 1 (PON1) gene.

Journal of affective disorders - 1 Jun 2012

Ezzaher Asma, Mouhamed Dhouha Haj, Mechri Anwar, Neffati Fadoua, Rejeb Jihéne, Omezzine Asma, Douki Wahiba, Bouslama Ali, Gaha Lotfi, Najjar Mohamed Fadhel

Abstract excerpt

BACKGROUND: The purpose of this work was to study the association between the PON1 L55M and Q192R polymorphisms and bipolar I disorder in Tunisian patients and to explore their relation to the sociodemographic, clinical and therapeutic characteristics of this disease. PATIENTS AND METHODS: Our st...

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Source

Identifiers

PMID: 21783258
DOI: 10.1016/j.jad.2011.06.029

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21783258-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

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Association between bipolar I disorder and the L55M and Q192R polymorphisms of the paraoxonase 1 (PON1) gene.PMID 21783258Read ↗

Evaluation of paraoxonase 1 polymorphisms in patients with bipolar disorder.Semantic proximity Read ↗

Lowered plasma paraoxonase (PON)1 activity is a trait marker of major depression and PON1 Q192R gene polymorphism-smoking interactions differentially predict the odds of major depression and bipolar disorder.Semantic proximity Read ↗

Association between polymorphisms of TLR2-1-6 and bipolar disorder in a tunisian population.Semantic proximity Read ↗

Paraoxonase 1 status and interactions between Q192R functional genotypes by smoking contribute significantly to total plasma radical trapping antioxidant potential.Semantic proximity Read ↗

The paraoxonase L55M and Q192R gene polymorphisms and myocardial infarction in a Tunisian population.Semantic proximity Read ↗

Association of PON1-L55M Genetic Variation with Idiopathic Male Infertility in an Iranian Population: A Case-Control StudySemantic proximity Read ↗

[Phenotypic Variants of Paraoxonase Q192R in Bipolar Disorder,Depression and Schizophrenia].Semantic proximity Read ↗

Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life.Semantic proximity Read ↗

The relationship of PON1 QR 192 and LM 55 polymorphisms with serum paraoxonase activities of Turkish diabetic patients.Semantic proximity Read ↗

Paraoxonase-1 55/192 genotypes in schizophrenic patients and their relatives in Turkish population.Semantic proximity Read ↗

Paraoxonase 1 (PON1)-L55M among common variants in the coding region of the paraoxonase gene family may contribute to the glycemic control in type 2 diabetes.Semantic proximity Read ↗

Genetic variation at Q192R and L55M polymorphisms in PON1.Semantic proximity Read ↗

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