Article
The HLA-G Genetic Contribution to Bipolar Disorder: A Trans-Ethnic Replication.
Immunological investigations - 1 Aug 2018
Sundaresh Aparna, Wu Ching-Lien, Chinnadurai Raj Kumar, Rajkumar Ravi Philip, Mariaselvam Christina Mary, LeMaoult Joël, Krishnamoorthy Rajagopal, Leboyer Marion, Negi Vir Singh, Tamouza Ryad
Abstract excerpt
Bipolar disorder (BD) is frequently associated with immune dysfunctions. Studying the genetic diversity of the immuno-modulatory human leukocyte antigen (HLA)-G locus in a French BD cohort, we previously reported an association between a functionally relevant 14 bp Ins/Del polymorphism and BD risk. The present study investigated the genetic and expression diversities of HLA-G in a geographically distinct South...
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