Article
Polymorphism of Toll-like receptor 4 gene in bipolar disorder.
Journal of affective disorders - 1 Jan 2014
Oliveira José, Busson Marc, Etain Bruno, Jamain Stéphane, Hamdani Nora, Boukouaci Wahid, Amokrane Kahina, Bennabi Mériem, Le Guen Emmanuel, Dargél Aroldo Ayub, Houenou Josselin, Ivanova Rayna, Bellivier Frank, Henry Chantal, Kahn Jean-Pierre, Charron Dominique, Krishnamoorthy Rajagopal, Vervoitte Laetitia, Leboyer Marion, Tamouza Ryad
Abstract excerpt
BACKGROUND: Bipolar disorder (BD) is considered as a multifactorial disorder involving complex interactions between genetic and environmental factors, where immune dysfunction is thought to play a key etiopathogenic role. In particular, excess of winter births associated with early-life infections raise the possibility of the implication of innate immunity. Given the pivotal role of Toll-like receptor 4 (TLR-4),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.