Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Physiological phenotypes have optimal values relevant to healthy aging: sweet spots deduced from the Canadian Longitudinal Study on Aging.

GeroScience - 1 Apr 2024

Vishnyakova Olga, Song Xiaowei, Rockwood Kenneth, Elliott Lloyd T, Brooks-Wilson Angela

Abstract excerpt

Previous observations on a group of exceptionally healthy "Super-Seniors" showed a lower variance of multiple physiological measures relevant for health than did a less healthy group of the same age. The finding was interpreted as the healthier individuals having physiological measurement values closer to an optimal level, or "sweet spot." Here, we tested the generalizability of the sweet-spot hypothesis in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Canada
Share to Longitudinal Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 37688655
DOI: 10.1007/s11357-023-00895-2
PMCID: PMC10828371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Physiological phenotypes have optimal values relevant to healthy aging: sweet spots deduced from the Canadian Longitudinal Study on Aging.PMID 37688655Read ↗

Clinical biomarkers and associations with healthspan and lifespan: Evidence from observational and genetic data.Semantic proximity Read ↗

Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition.Semantic proximity Read ↗

Physiological Phenotypic Aging Index and Its Association With Health, Functional, and Health Care Outcomes in Older Adults: Findings From the UK Biobank.Semantic proximity Read ↗

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity.Semantic proximity Read ↗

Identification of 12 genetic loci associated with human healthspanSemantic proximity Read ↗

An Objective Metric of Individual Health And Aging For Population SurveysSemantic proximity Read ↗

Heritability of and mortality prediction with a longevity phenotype: the healthy aging index.Semantic proximity Read ↗

Engaging the complexity of diet and healthy aging in humansSemantic proximity Read ↗

Heritability estimates of endophenotypes of long and health life: the Long Life Family Study.Semantic proximity Read ↗

The healthy aging phenotype in older people in ManizalesSemantic proximity Read ↗

Oxidative Stress Factors Mediate the Association Between Life’s Essential 8 and Accelerated Phenotypic Aging: NHANES 2005–2018Semantic proximity Read ↗

Development of a Multi-Trait Polygenic Score for Intrinsic CapacitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.