Article
Heritability estimates of endophenotypes of long and health life: the Long Life Family Study.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Dec 2010
Matteini Amy M, Fallin M Daniele, Kammerer Candace M, Schupf Nicole, Yashin Anatoli I, Christensen Kaare, Arbeev Konstantin G, Barr Graham, Mayeux Richard, Newman Anne B, Walston Jeremy D
Abstract excerpt
BACKGROUND: Identification of gene variants that contribute to exceptional survival may provide critical biologic information that informs optimal health across the life span. METHODS: As part of phenotype development efforts for the Long Life Family Study, endophenotypes that represent exceptional survival were identified and heritability estimates were calculated. Principal components (PCs) analysis was carried...
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