Article
Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity.
Experimental gerontology - 1 Sept 2016
Deelen Joris, van den Akker Erik B, Trompet Stella, van Heemst Diana, Mooijaart Simon P, Slagboom P Eline, Beekman Marian
Abstract excerpt
Genetic studies have thus far identified a limited number of loci associated with human longevity by applying age at death or survival up to advanced ages as phenotype. As an alternative approach, one could first try to identify biomarkers of healthy ageing and the genetic variants associated with these traits and subsequently determine the association of these variants with human longevity. In the present study,...
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