Article
Clinical biomarkers and associations with healthspan and lifespan: Evidence from observational and genetic data.
EBioMedicine - 1 Apr 2021
Li Xia, Ploner Alexander, Wang Yunzhang, Zhan Yiqiang, Pedersen Nancy L, Magnusson Patrik Ke, Jylhävä Juulia, Hägg Sara
Abstract excerpt
BACKGROUND: Biomarker-disease relationships are extensively investigated. However, associations between common clinical biomarkers and healthspan, the disease-free lifespan, are largely unknown. We aimed to explore the predictive values of ten biomarkers on healthspan and lifespan, and to identify putative causal mechanisms. METHODS: Using data from 12,098 Swedish individuals aged 47-94 years, we examined both...
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