Article
Risk of endometrial cancer after RRSO in BRCA 1/2 carriers: a multicentre cohort study.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Apr 2024
Pla-Juher Helena, Pardo Marta, Izquierdo Àngel J, Darder Esther, Carbó Anna, Munté Elisabet, Torres-Esquius Sara, Balmaña Judith, Lázaro Concepción, Brunet Joan M, Barretina-Ginesta Maria-Pilar
Abstract excerpt
OBJECTIVE: To know the risk of endometrial cancer (EC) in a population of women with BRCA 1/2 pathogenic or likely pathogenic variants after risk-reducing salpingo-oophorectomy (RRSO). METHODS: The study cohort included data from 857 women with BRCA mutations who underwent RRSO visited four hospitals in Catalonia, Spain, from January 1, 1999 to April 30, 2019. Standardized incidence ratio (SIR) of EC was...
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