Article
Endometrium is not the primary site of origin of pelvic high-grade serous carcinoma in BRCA1 or BRCA2 mutation carriers.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2013
Reitsma Welmoed, Mourits Marian J E, de Bock Geertruida H, Hollema Harry
Abstract excerpt
Serous endometrial intraepithelial carcinoma has been proposed to be a potential precursor lesion of pelvic high-grade serous carcinoma. If true, an increased incidence of uterine papillary serous carcinomas would be expected in BRCA1 and BRCA2 mutation carriers, who are at high-risk of developing pelvic high-grade serous carcinoma. This study explored particularly the occurrence of uterine papillary serous...
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