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The Growing Relevance of Immunoregulation in Pediatric Brain Tumors

9 Nov 2021

Abstract excerpt

Pediatric brain tumors are genetically heterogeneous solid neoplasms. With a prevailing poor prognosis and widespread resistance to conventional multimodal therapy, these aggressive tumors are the leading cause of childhood cancer-related deaths worldwide. Advancement in molecular research revealed their unique genetic and epigenetic characteristics and paved the way for more defined prognostication and targeted...

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PMID: 34830753
DOI: 10.3390/cancers13225601

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