Article
Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response.
Journal of neuro-oncology - 1 Apr 2018
Plant Ashley S, Koyama Shohei, Sinai Claire, Solomon Isaac H, Griffin Gabriel K, Ligon Keith L, Bandopadhayay Pratiti, Betensky Rebecca, Emerson Ryan, Dranoff Glenn, Kieran Mark W, Ritz Jerome
Abstract excerpt
There is little known regarding the immune infiltrate present in pediatric brain tumors and how this compares to what is known about histologically similar adult tumors and its correlation with survival. Here, we provide a descriptive analysis of the immune infiltrate of 22 fresh pediatric brain tumor tissue samples of mixed diagnoses and 40 peripheral blood samples. Samples were analyzed using a flow cytometry...
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