Article
Integrating genomics and proteomics data to identify candidate plasma biomarkers for lung cancer risk among European descendants.
British journal of cancer - 1 Oct 2023
Yang Yaohua, Xu Shuai, Jia Guochong, Yuan Fangcheng, Ping Jie, Guo Xingyi, Tao Ran, Shu Xiao-Ou, Zheng Wei, Long Jirong, Cai Qiuyin
Abstract excerpt
BACKGROUND: Plasma proteins are potential biomarkers for complex diseases. We aimed to identify plasma protein biomarkers for lung cancer. METHODS: We investigated genetically predicted plasma levels of 1130 proteins in association with lung cancer risk among 29,266 cases and 56,450 controls of European descent. For proteins significantly associated with lung cancer risk, we evaluated associations of genetically...
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