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Article

Exploration of plasma genetic markers mediating lung cancer-induced cardiovascular disorders based on genome wide association studies.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2025

Wang Tongyu, Miao Xinge, Wang Yin, Chandran Sadees Clarance, Xia Yunlong

Abstract excerpt

Lung cancer is strongly associated with increased cardiovascular disease (CVD) risk, yet the molecular mechanisms remain poorly understood. Batched two-sample Mendelian randomization (MR) analysis was performed to investigate cancer types and CVDs with significant associations. Local genetic correlation analyses were performed to identify meaningful genetic regions. Genomic Structural Equation Modeling (gSEM) was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40973822
DOI: 10.1007/s00335-025-10158-4

Genes

KRTCAP2
ZBTB7B
CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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