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Identification of novel pQTL-SNPs associated with lung adenocarcinoma risk: A multi-stage study.

Cancer medicine - 1 Sept 2024

Wu Yutong, Xu Huiwen, Mao Liping, Zhao Rongrong, Chu Junfeng, Huang Lili, Zhang Wendi, Liu Yiran, Chen Qiong, Tao Xiaobo, Li Siqi, Zhou Shenxuan, Ning Anhui, Li Zhenyu, Tian Tian, Zhang Lei, Cui Jiahua, Tian Guangyu, Chu Minjie

Abstract excerpt

BACKGROUND AND OBJECTIVE: To explore the association between protein quantitative trait loci (pQTL-SNPs) and the risk of LUAD. METHODS: "Blood +" high depth blood proteomics analysis was performed on plasma from female LUAD patients and female healthy controls, and combined with proteomics data from tumors and adjacent non-tumor tissues of female LUAD patients to screen proteins uniformly expressed in plasma and...

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Identifiers

PMID: 39291803
DOI: 10.1002/cam4.70247
PMCID: PMC11409194

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