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Machine learning-based proteogenomic data modeling identifies circulating plasma biomarkers for early detection of lung cancer

2024-08-01

Abstract excerpt

Identifying genetic variants associated with lung cancer (LC) risk and their impact on plasma protein levels is crucial for understanding LC predisposition. The discovery of risk biomarkers can enhance early LC screening protocols and improve prognostic interventions. In this study, we performed a genome-wide association analysis using the UK Biobank and FinnGen. We identified genetic variants associated with LC a...

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Literature Corpus work
3626bcd2-793d-5a52-9c7a-8ab211084078
DOI
10.1101/2024.07.30.24311241
Open publication

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Machine learning-based proteogenomic data modeling identifies circulating plasma biomarkers for early detection of lung cancerDOI 10.1101/2024.07.30.24311241
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