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Article

Identification of the CeRNA axis of circ_0000006/miR-483-5p/KDM2B in the progression of aortic aneurysm to aorta dissection.

BMC cardiovascular disorders - 28 Feb 2025

Liu Yong, Tan Xiong, Wang Liang, Jin Weitao, He Yangchen, Yan Yu, Hu Kai, Wang Hao, Xiang Chaohu, Hou Ming, Lai Yinglong

Abstract excerpt

BACKGROUND: Aortic aneurysm (AA) and aortic dissection (AD) are serious cardiovascular disorders with a high risk of mortality. The molecular mechanisms underlying the progression from AA to AD are not well understood. This study aimed to identify the key circular RNA (circRNA)-microRNA (miRNA)-messenger RNA (mRNA) regulatory axis involved in this disease progression. METHODS: CircRNA microarray, miRNA...

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Share to Aortic Aneurysm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Regulatory Networks

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Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to RNA, Circular

Source

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Identifiers

PMID: 40021969
DOI: 10.1186/s12872-025-04598-8
PMCID: PMC11869725

Genes

KDM2B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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